Last year's semi-finalists Marcelo Arevalo and Jean-Julien Rojer continued their US Open run on Friday when they defeated Matteo Arnaldi and Bart Stevens 6-2, 6-3.
The fourth seeds, who triumphed at Roland Garros together in 2022, dropped just one point on first serve to advance after 61 minutes. Arevalo and Rojer will next face Lloyd Glasspool and Harri Heliovaara or Robert Galloway and Albano Olivetti in the third round.
Top seeds Wesley Koolhof and Neal Skupski overcame 2019 champions Juan Sebastian Cabal and Robert Farah 7-6(2), 1-6, 6-3 in two hours and 36 minutes. The Dutch-British team, who won the Wimbledon title in July, next play Nathaniel Lammons and Jackson Withrow.
The Americans, who won their third tour-level title of the season together in Winston-Salem last week, defeated Ariel Behar and Adam Pavlasek 7-6(3), 6-4.
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Rohan Bopanna and Matthew Ebden downed Andrey Golubev and Roman Safiullin 6-3, 6-3, while Britons Julian Cash and Henry Patten beat Gregoire Barrere and Quentin Halys 7-6(3), 6-3. Sixth seeds Bopanna and Ebden play Cash and Patten in the third round.
The 2015 champions Pierre-Hugues Herbert and Nicolas Mahut defeated Jamie Murray and Michael Venus 6-4, 6-4. The French team will next meet Marcel Granollers and Horacio Zeballos after the eighth seeds moved past Lloyd Harris and Miomir Kecmanovic 7-5, 6-4.